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1

Development and validation of stability indicating HPLC methods for related substances and assay analyses of amoxicillin and potassium clavulanate mixtures

Bellur Atici, Esen, Yazar, Yücel, Ağtaş, Çağan, Ridvanoğlu, Nurten, Karlığa, Bekir

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2017

Langue:

english

Fichier:

PDF, 1.10 MB

english, 2017

2

Identification, synthesis and characterization of process related impurities of benidipine hydrochloride, stress-testing/stability studies and HPLC/UPLC method validations

Bellur Atici, Esen, Karlığa, Bekir

Journal:

Journal of Pharmaceutical Analysis

Année:

2015

Langue:

english

Fichier:

PDF, 1.33 MB

english, 2015

3

Quantitative determination of two polymorphic forms of imatinib mesylate in a drug substance and tablet formulation by X-ray powder diffraction, differential scanning calorimetry and attenuated total reflectance Fourier transform infrared spectroscopy

Bellur Atici, Esen, Karlığa, Bekir

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2015

Langue:

english

Fichier:

PDF, 3.34 MB

english, 2015

4

Chemoselective, Regioselective, and E/Z-Diastereoselective Synthesis of 2-Alkylidenetetrahydrofurans by Sequential Reactions of Ambident Dianions and Monoanions.

Peter Langer, Esen Bellur

Journal:

Année:

2004

Fichier:

PDF, 273 KB

2004

5

Reaction of 2-Alkylidenetetrahydrofurans with Boron Tribromide: Chemo- and Regioselective Synthesis of 6-Bromo-3-oxoalkanoates by Application of a “Cyclization-Ring-Opening” Strategy.

Esen Bellur, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 23 KB

2005

6

Functionalization of 2-Alkylidenetetrahydrofurans and 2-Alkylidenepyrrolidines by Palladium(0)-Catalyzed Cross-Coupling Reactions.

Esen Bellur, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 34 KB

2005

7

Efficient Synthesis of Functionalized Furans and Benzofurans Based on a “[3 + 2] Cyclization/Oxidation” Strategy.

Esen Bellur, Ilia Freifeld, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 36 KB

2005

8

Regioselective Synthesis of Functionalized Furans by Cyclization of 1,3-Bis-silyl Enol Ethers with 1-Chloro-2,2-dimethoxyethane.

Esen Bellur, Helmar Goerls, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 45 KB

2005

9

Convenient Synthesis of ε-Halo-β-ketoesters and γ,γ′-Dibromoalkanones by Regio- and Chemoselective Reaction of 2-Alkylidenetetrahydrofurans with Boron Trihalides: A “Ring-Closure/Ring-Cleavage” Strategy.

Esen Bellur, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 38 KB

2005

10

Synthesis of 2-Alkylidenepyrrolidines, Pyrroles and Indoles by Condensation of Silyl Enol Ethers and 1,3-Bis-Silyl Enol Ethers with 1-Azido-2,2-dimethoxyethane and Subsequent Reductive Cyclization.

Esen Bellur, Helmar Goerls, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 39 KB

2005

11

Synthesis of 2-Alkylidenepyrrolidines, Pyrroles and Indoles by Condensation of Silyl Enol Ethers and 1,3-Bis-Silyl Enol Ethers with 1-Azido-2,2-dimethoxyethane and Subsequent Reductive Cyclization.

Esen Bellur, Helmar Goerls, Peter Langer

Journal:

Année:

2005

Fichier:

PDF, 36 KB

2005

12

Synthesis of Benzofurans with Remote Bromide Functionality by Domino “Ring-Cleavage-Deprotection-Cyclization” Reactions of 2-Alkylidenetetrahydrofurans with Boron Tribromide.

Esen Bellur, Peter Langer

Journal:

Année:

2006

Fichier:

PDF, 36 KB

2006

13

Regioselective Synthesis of Functionalized Furans by Cyclization of 1,3-Bis-Silyl Enol Ethers with 1-Chloro-2,2-dimethoxyethane

Esen Bellur, Helmar Görls, Peter Langer

Journal:

European Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 267 KB

english, 2005

14

Synthesis of Functionalized 2-Alkylidene-tetrahydrofurans Based on a [3+2] Cyclization/Bromination/Palladium(0) Cross-Coupling Strategy

Esen Bellur, Peter Langer

Journal:

European Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 248 KB

english, 2005

15

Synthesis of (tetrahydrofuran-2-yl)acetates based on a ‘cyclization/hydrogenation/enzymatic kinetic resolution’ strategy

Esen Bellur, Ilia Freifeld, Dominique Böttcher, Uwe T. Bornscheuer, Peter Langer

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 326 KB

english, 2006

16

Synthesis of 4-(3-hydroxyalkyl)pyrimidines by ring transformation reactions of 2-alkylidenetetrahydrofurans with amidines

Esen Bellur, Peter Langer

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 278 KB

english, 2006

17

Synthesis of 2,5-dihydrobenzo[b]oxepins and 5,6-dihydro-2H-benzo[b]oxocines based on [3+3] cyclizations of 1,3-bis(silyl enol ethers)

Van Thi Hong Nguyen, Esen Bellur, Christine Fischer, Peter Langer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 286 KB

english, 2007

18

Recent advances in the chemistry of 2-(2-oxoalkylidene)tetrahydrofurans

Esen Bellur, Holger Feist, Peter Langer

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 2.65 MB

english, 2007

19

Enantioselective synthesis of 2-alkylidenetetrahydrofurans based on a ‘cyclization/enzymatic resolution’ strategy

Esen Bellur, Dominique Böttcher, Uwe Bornscheuer, Peter Langer

Journal:

Tetrahedron: Asymmetry

Année:

2006

Langue:

english

Fichier:

PDF, 188 KB

english, 2006

20

Efficient synthesis of functionalized furans and benzofurans based on a ‘[3+2] cyclization/oxidation’ strategy

Esen Bellur, Ilia Freifeld, Peter Langer

Journal:

Tetrahedron Letters

Année:

2005

Langue:

english

Fichier:

PDF, 116 KB

english, 2005

21

Synthesis of 2,5-dihydrobenzo[b]oxepines and 5,6-dihydro-2H-benzo[b]oxocines based on a ‘[3+3] cyclization-olefin-metathesis’ strategy

Van Thi Hong Nguyen, Esen Bellur, Peter Langer

Journal:

Tetrahedron Letters

Année:

2006

Langue:

english

Fichier:

PDF, 120 KB

english, 2006

22

Synthesis of functionalized pyrroles and 6,7-dihydro-1H-indol-4(5H)-ones by reaction of 1,3-dicarbonyl compounds with 2-azido-1,1-diethoxyethane

Esen Bellur, Peter Langer

Journal:

Tetrahedron Letters

Année:

2006

Langue:

english

Fichier:

PDF, 115 KB

english, 2006

23

Synthesis of 2-Alkylidenepyrrolidines, Pyrroles, and Indoles by Condensation of Silyl Enol Ethers and 1,3-Bis-Silyl Enol Ethers with 1-Azido-2,2-dimethoxyethane and Subsequent Reductive Cyclization

Bellur, Esen, Görls, Helmar, Langer, Peter

Journal:

Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 226 KB

english, 2005

24

Domino Reactions of 1,2-Diimidoyl-1,2-dichloroethanes. Synthesis of 3-Imino-1,2-dithia-3 H -cyclopent-4-enes, 3-Amino-2-thioxo-2,5 H -pyrrol-5-ones, 2,3-Diamino-4-thioxo-4 H -thiopyrans, and 6-Imino-6 H -1,3-oxazines

Bellur, Esen, Görls, Helmar, Langer, Peter

Journal:

Journal of Organic Chemistry

Année:

2006

Langue:

english

Fichier:

PDF, 119 KB

english, 2006

25

Chemoselective, Regioselective, and E / Z -Diastereoselective Synthesis of 2-Alkylidenetetrahydrofurans by Sequential Reactions of Ambident Dianions and Monoanions

Langer, Peter, Bellur, Esen

Journal:

Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 75 KB

english, 2003

26

Highly Enantioselective Hydrogenation of β‐Alkyl and β‐(ω‐Chloroalkyl) Substituted β‐Keto Esters

Karamé, Iyad, Bellur, Esen, Rotzoll, Sven, Langer, Peter, Fischer, Christine, Holz, Jens, Börner, Armin

Journal:

Synthetic Communications

Année:

2007

Langue:

english

Fichier:

PDF, 118 KB

english, 2007

27

Convenient Synthesis of ε-Halo-β-ketoesters and γ,γ‘-Dibromoalkanones by Regio- and Chemoselective Reaction of 2-Alkylidenetetrahydrofurans with Boron Trihalides: A “Ring-Closure/Ring-Cleavage” Strategy

Bellur, Esen, Langer, Peter

Journal:

Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 145 KB

english, 2005

28

Efficient Synthesis of Furan-2-ylacetates, 7-(Alkoxycarbonyl)benzofurans, and 7-(Alkoxycarbonyl)-2,3-dihydrobenzofurans Based on Cyclization Reactions of Free and Masked Dianions: A “Cyclization/Dehydrogenation” Strategy

Bellur, Esen, Langer, Peter

Journal:

Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 314 KB

english, 2005

29

Synthesis of Benzofurans with Remote Bromide Functionality by Domino “Ring-Cleavage-Deprotection-Cyclization” Reactions of 2-Alkylidenetetrahydrofurans with Boron Tribromide

Bellur, Esen, Langer, Peter

Journal:

Journal of Organic Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 189 KB

english, 2005

30

Identification, synthesis and characterization of process related desfluoro impurity of ezetimibe and HPLC method validations

Bellur Atici, Esen, Karlıg˘a, Bekir

Journal:

Journal of Pharmaceutical Analysis

Année:

2015

Langue:

english

Fichier:

PDF, 2.32 MB

english, 2015

31

Reaction of 2-Alkylidenetetrahydrofurans with Boron Tribromide: Chemo- and Regioselective Synthesis of 6-Bromo-3-oxoalkanoates by Application of a ‘Cyclization-Ring-Opening’ Strategy

Bellur, Esen, Langer, Peter

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 103 KB

english, 2004

32

Synthesis of 4-Alkyl- and 4-(ω-Chloroalkyl)-3-hydroxy-5-alkylidenebutenolides Based On Cyclizations of 4-Alkyl- and 4-(ω-Chloroalkyl)-1,3-bis(trimethylsilyloxy)buta-1,3-dienes with Oxalyl Chloride

Nguyen, Van, Bellur, Esen, Appel, Bettina, Langer, Peter

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 155 KB

english, 2006

33

Synthesis of 3-Acylpyrroles, 3-(Alkoxycarbonyl)pyrroles, 1,5,6,7-Tetrahydro-4H-indol-4-ones and 3-Benzoylpyridines Based on Staudinger-Aza-Wittig Reactions of 1,3-Dicarbonyl Compounds with 2- and 3-Azido-1,1-dialkoxyalkanes

Bellur, Esen, Yawer, Mirza, Hussain, Ibrar, Riahi, Abdolmajid, Fatunsin, Olumide, Fischer, Christine, Langer, Peter

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 279 KB

english, 2009

34

Functionalization of 2-Alkylidenetetrahydrofurans and 2-Alkylidenepyrrolidines by Palladium(0)-Catalyzed Cross-Coupling Reactions

Bellur, Esen, Langer, Peter

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 102 KB

english, 2004

35

Synthesis of Functionalized Furans Based on a ‘[3+2] Cyclization/Bromination/Elimination’ Strategy

Bellur, Esen, Langer, Peter

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 207 KB

english, 2006

36

Synthesis of 3-Alkyl- and 3-Chloroalkyl-2-hydroxybenzoates Based on [3+3] Cyclizations of 4-Alkyl- and 4-Chloroalkyl-1,3-bis(trimethylsilyloxy)buta-1,3-dienes

Nguyen, Van Thi, Bellur, Esen, Appel, Bettina, Langer, Peter

Journal:

Année:

2006

Langue:

english

Fichier:

PDF, 164 KB

english, 2006

37

Synthesis and characterization of oxitropium bromide related substances and novel stability indicating HPLC methods

Bellur Atici, Esen, AÄtaÅ, ÃaÄan, Yazar, YÃ¼cel, RÄ±dvanoÄlu, Nurten

Journal:

Journal of Pharmaceutical and Biomedical Analysis

Année:

2020

Fichier:

PDF, 3.51 MB

2020